This edited book is based on the accepted papers for presentation at the 1st MedGU Annual Meeting, Istanbul, 2021. With two parts spanning a large spectrum of environmental, geomorphological and geoarcheological topics and a third part on caves and karst, which includes research studies gathered on the occasion of the International Year of Caves and Karst (2021), this book presents a series of newest research studies that are nowadays relevant to Middle East, Mediterranean region, and Africa. The book gives a general overview on current research, focusing on geoenvironmental issues and challenges in environmental management in the Middle East and Mediterranean region and surrounding areas. It offers a broad range of recent studies that discuss the latest advances in geomorphology, landslides, soil science, paleoclimate, and geoarcheology. It also shares insights on cave and karst studies including speleology, cave and karst explorations, geomorphology, hydrogeology, geoethics, prehistoric eras in karst, geotectonics, and the nexus between human activities and karst sustainability.